ObaCell® ASC Fat-on-a-Chip Live Plate
ObaCell® was created as a tool for disease modeling and drug screening; moreover, it's a versatile plug-and-play system capable of seamless integration with other organ-on-a-chip models, offering boundless potential for transformative research and innovation.
ObaCell® ASC Fat-on-a-Chip Live Plate is a ready to use functional adipose organoid model provided to you in a 96-well plate format. Customize your model by choosing a unique cell donor(s) from our diverse inventory that best represents the prevalent population modeled in your study. Choose up to 4 cell donors per plate. A 3-week lead time is needed to initiate culture in our lab before delivering to you.
Endpoint analyses capable of this model include, but are not limited to, brightfield and fluorescent imaging, confocal microscopy, high-throughput microscopy, cell viability staining, metabolic activity assays via alamarblue or similar reagents, cell retrieval, histological staining, secretome analysis, cytokine profiles, and RNA and protein expression.
Model Highlights
- In-vitro self-assembled organoids
- Physiologically and functionally relevant human-derived adipose model
- Matrix protein profile supports cell growth, motility, and vascular response
Product Components
1 ready to use 3D adipose organoid model in a 96-well plate format.
92 tests
Consists of ASC embedded in our ObaGel® + ObaVate hydrogel scaffold and differentiated into pre-adipocytes for 2 weeks.
Product Formats
1 Cell Donor
Price $4,840
SKU OS-312-01
2 Cell Donors
Price $5,324
SKU OS-312-02
3 Cell Donors
Price $6,655
SKU OS-312-03
4 Cell Donors
Price $7,986
SKU OS-312-04
We suggest choosing a donor pool for pilot studies to lower variability of donor performance. Priced as 1 cell donor.
Companion Products
StromaQual3D™ Maintenance Media
AdipoQual3D™ Adipogenic Differentiation Media
ObaZolve™ Cell Retrieval Agent
ObaFlowTM Cell Retrieval Agent
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Relevant Publications
2024
Adipose Tissue in Breast Cancer Microphysioloigical Models to Capture Human Diversity in Preclinical Models. Int. J. Mol. Sci. 2024, 25, 2728.
2021
Adipose-derived cells: building blocks of three-dimensional microphysiological systems. Biomater Transl. 2021 Dec 28;2(4):301-306.
Human Adipose-Derived Stromal/Stem Cell Culture and Analysis Methods for Adipose Tissue Modeling In Vitro: A Systematic Review. Cells. 2021 Jun 3;10(6):1378.
2020
Human Adipose Derived Cells in Two- And Three-Dimensional Cultures: Functional Validation of an In Vitro Fat Construct. Stem Cells Int. 2020 Jun 10
Fat-on-a-Chip Models for Research and Discovery in Obesity and Its Metabolic Co-Morbidities Tissue Eng Part B Rev. 2020 Mar 26.
Adipose Tissue-Derived Stem Cells Retain Their Adipocyte Differentiation Potential in Three-Dimensional Hydrogels and Bioreactors. Biomolecules. 2020 Jul; 10(7): 1070.