Our Technology

Our product ecosystem includes human-derived hydrogels, human stem cells, and supporting cell culture mediums that seamlessly integrate to form our dynamic ObaCell® Fat-on-a-Chip models for pre-clinical drug development.

Current preclinical and clinical drug testing relies heavily on animal-derived data and research products.

• Animal models do not fully mimic human responses and lack differences in age, sex, ethnicity, and disease status.
• Animal-derived products, such as Matrigel-derived from mouse tumor tissue—are unreliable and often produce false results.
• Mouse tissue is in short supply and expensive, hampering the level of research required to address today’s health epidemics.

Current preclinical and clinical drug testing does not include representation of the diverse patient populations that these drugs are intended to treat.

• The lack of diversity in research has impeded progress in the fields of diabetes, obesity, cancer, heart disease, and wound healing.
• Minority populations are highly impacted by today’s research models and clinical trials.

3D Stem Cell-Based Discovery Tools Derived from human sources

• Obatala Sciences is the 1st to market a fully humanized microphysiological system representative of patients from varying demographics that can be used for drug screening and more.
• We are democratizing premium quality research tools by leveraging our extensive knowledge and years of research within adipose biology and regenerative medicine.
• We are converting routinely discarded medical waste to human tissue-derived stem cells, culture reagents, and 3D discovery tools.

Our Tools

human-derived stem cells

• We have a repository of 200+ cell donors that represent a diverse population and can be classified by age, sex, race, BMI, and disease state. These cells are incorporated into our Fat-on-a-Chip and Obesity-on-a-Chip models to represent targeted populations for drug screening.

Human-derived hydrogels

• Our ObaGel® matrices are derived from human tissues and designed to support functional organoid models that recapitulate the human in vivo environment in in vitro models.
• ObaGel® matrices excel in supporting and maintaining crucial functional characteristics of cells, including proliferation, differentiation, vascularization, and immunogenic responses, thereby surpassing the limitations inherent in traditional methods such as 2D culture and the use of single-source or single-protein matrices.

Cell Culture Media

• We offer cell culture medias specially formulated to support maintenance and multi-lineage differention of human mesenchymal stem cells. These mediums pair seamlessly with our cells, hydrogels, and organ-on-chip models.

Our Models

ObaCell fat-on-a-Chip & Obesity-on-a-chip:

• Engineered micro-tissues that reproduce human biology​
• Demonstrated reliable alternatives to animal testing​
• Validated to accurately predict human toxicity, safety, and efficacy

Our Models:

• Improve the drug success rates by identifying the failing drugs faster.
• Accelerate the conversion from animal testing to more effective human testing.
• Bring clinically relevant human-based data to drug developers.
• Are representative of tissue populations that are hard to access.