Services: ObaCell® Obesity-on-a-Chip

ObaCell® Obesity-on-a-Chip, is a next-gen advancement for researchers seeking to redefine drug discovery in metabolic diseases. This innovative platform offers an unparalleled opportunity to emulate the intricate physiology of an obese individual in a fraction of the time, accelerating the pace of research and enabling swift identification of promising drug candidates.

Product Uses

• Optimized Drug Discovery: ObaCell® Obesity-on-a-Chip facilitates efficient screening of potential therapeutics, allowing researchers to make informed decisions rapidly and effectively, save resources, and expedite time to market.

Key Features

• 3D Cellular System: Human adipose-derived stromal/stem cells differentiated into adipocytes with large lipid droplets, offering a metabolically active adipose model responsive to GLP-1 drugs.
• Adipocyte Hypertrophy Simulation: Increased lipid size mimics adipocyte hypertrophy, providing a more accurate representation of obese physiology. Model also simulates fasting/feeding.
• Enhanced Metabolic Function: Replicates human adipose tissue metabolism, facilitating precise drug screening and research.
• Dynamic Compatibility: Highly compatible with functional assays and dynamic outputs, ensuring reliable and reproducible experimental results.
• Customizable: Allows for selection of unique cell donors from our diverse inventory to match the prevalent population modeled in your study

Endpoint Services

• Lipid Droplet Quantification

• Metabolic Activity

• Cell Viability Staining

• Secretome Analysis

• Cytokine Profiles

• RNA and Protein Expression

• Lipolysis

• Glucose Uptake

• Microscopy

  • Bright-field

  • Fluorescent

  • Confocal

  • High-Throughput

Service Inquiry

Please fill out and submit the form below with details regarding your service request for this model. Our Sales team will return your response asap. If you incur any issues with the form, please email orders@obatalasciences.com

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Relevant Publications

ObaCell® Obesity-on-a-Chip Product Sheet

Licensed Technology

Fattening chips: hypertrophy, feeding, and fasting of human white adipocytes in vitro, Lab Chip, 2020, 20, 4152-4165